Anti-Bovine PKC Agarose

Cat# P110-1

Size : 1ml

Brand : Leinco Technologies

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AntiBovine PKC Agarose

Product No.: P110

[product_table name="All Top" skus="P110"]

Clone
MC5
Target
Protein Kinase C
Formats AvailableView All
Product Type
Monoclonal Antibody
Isotype
IgG2a

Antibody Details

Product Details

Reactive Species
Bovine
Host Species
Mouse
Formulation
AntiProtein Kinase CAgarose is supplied in 0.01 M phosphate buffered saline (PBS) pH 7.2, 0.09% sodium azide as a preservative.
Storage and Handling
Stable when stored at 2 8°C.
Country of Origin
USA
Shipping
Next Day Ambient
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Description

Specificity
AntiProtein Kinase C (PKC) recognizes the intact (Mr 7980 kDa) calciumactivated, phospholipiddependent Protein Kinase C in bovine brain. The antibody strongly crossreacts with PKC in human, mouse and rat cells.1 AntiPKC (clone MC5) binds to an epitope at the hinge region of the enzyme, the site of phorbolesterinduced proteolysis which is thought to downregulate PKC activity in intact cells.1,2 Monoclonal MC5 reacts with PKCα/ß12 isoforms.
Background
AntiProtein Kinase C (PKC) has been covalently conjugated to 4% crosslinked agarose using conjugation chemistries to reduce nonspecific binding and optimize binding of Protein Kinase C. AntiProtein Kinase CAgarose may be used to isolate Protein Kinase C.

Bead Size
75300 µm (50200 mesh)
Research Area
Apoptosis
.
Cell Biology
.
Immunology

References & Citations

Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.
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