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> Cholesteryl linoleate [604-33-1]

Cholesteryl linoleate [604-33-1]

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Cat# HY-W010697-100mg

Size : 100mg

Brand : MedChemExpress


Cholesteryl linoleate is shown to be the major cholesteryl ester contained in LDL and atherosclerotic lesions.

For research use only. We do not sell to patients.

Cholesteryl linoleate Chemical Structure

Cholesteryl linoleate Chemical Structure

CAS No. : 604-33-1

This product is a controlled substance and not for sale in your territory.

Based on 1 publication(s) in Google Scholar

Description

Cholesteryl linoleate is shown to be the major cholesteryl ester contained in LDL and atherosclerotic lesions.

IC50 & Target

Human Endogenous Metabolite

 

Molecular Weight

649.10

Formula

C45H76O2
CAS No.

604-33-1
Appearance

Solid

Color

White to off-white

SMILES

CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(02)[C@]3(02)CC=C4C[C@@H](OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)CC[C@]4(C)[C@@]3(02)CC[C@]12C
Structure Classification
  • Steroids
Initial Source
  • Endogenous metabolite
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (77.03 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5406 mL 7.7030 mL 15.4059 mL
5 mM 0.3081 mL 1.5406 mL 3.0812 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

COA (244 KB) HNMR (142 KB)

Handling Instructions (2659 KB)
References

  • [1]. Huber J, et al. Oxidized cholesteryl linoleates stimulate endothelial cells to bind monocytes via the extracellular signal-regulated kinase 1/2 pathway. Arterioscler Thromb Vasc Biol. 2002 Apr 1;22(4):581-6.  [Content Brief]

  • [1]. Huber J, et al. Oxidized cholesteryl linoleates stimulate endothelial cells to bind monocytes via the extracellular signal-regulated kinase 1/2 pathway. Arterioscler Thromb Vasc Biol. 2002 Apr 1;22(4):581-6.

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.5406 mL 7.7030 mL 15.4059 mL 38.5149 mL
5 mM 0.3081 mL 1.5406 mL 3.0812 mL 7.7030 mL
10 mM 0.1541 mL 0.7703 mL 1.5406 mL 3.8515 mL
15 mM 0.1027 mL 0.5135 mL 1.0271 mL 2.5677 mL
20 mM 0.0770 mL 0.3851 mL 0.7703 mL 1.9257 mL
25 mM 0.0616 mL 0.3081 mL 0.6162 mL 1.5406 mL
30 mM 0.0514 mL 0.2568 mL 0.5135 mL 1.2838 mL
40 mM 0.0385 mL 0.1926 mL 0.3851 mL 0.9629 mL
50 mM 0.0308 mL 0.1541 mL 0.3081 mL 0.7703 mL
60 mM 0.0257 mL 0.1284 mL 0.2568 mL 0.6419 mL
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Cholesteryl linoleate Related Classifications

  • Metabolic Disease
  • Metabolic Enzyme/Protease
  • Endogenous Metabolite
Help & FAQs

Keywords:

Cholesteryl linoleate604-33-1Endogenous MetaboliteInhibitorinhibitorinhibit