Galanthus nivalis (GNL/GNA)

Purified by affinity chromatography, Galanthus nivalis lectin (GNL/GNA) is composed of four identical subunits. GNL is a mannose-binding lectin, though [interestingly] it will not bind alpha-linked glucose. This lectin was one of the original molecules used to understand how proteins recognize carbohydrates. Galanthus nivalis is found to bind to many viral glycoproteins, making it a useful tool in HIV research studies.

Carbohydrate Specificity:
alpha-Mannose

Inhibitory Carbohydrate:
Mannose-alpha (1,3) > Mannose

Divalent Ions:
None Required

Activity:
<15ug/ml will agglutinate human type O erythrocytes

Storage and Stability:
Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.