Guinea Pig Polyclonal Anti-Keratin K5

Cat# GP-CK5

Size : 100µL

Brand : Progen


anti-Keratin K5 guinea pig polyclonal, serum

Product: anti-Keratin K5 guinea pig polyclonal, serum
Art.No.: GP-CK5

Quantity 100 µl
Antibody Type Polyclonal
Host Guinea pig
Conjugate Unconjugated
Application IHC, WB
Purification Stabilized antiserum
Reactivity Bovine, Human, Mouse
Storage Short term at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/thaw cycles
Intended use Research use only
Immunogen Recombinant human keratin K5
Formulation Contains 0.09% sodium azide and 0.5% BSA
UniprotID Q5XQN5 (Bovine), Q7RTS7 (Human), Q922U2 (Mouse)
Synonym Keratin, type II cytoskeletal 74, Cytokeratin-74, CK-74, Keratin-5c, K5C, Keratin-74, K74, Type II inner root sheath-specific keratin-K6irs4, Type-II keratin Kb37, KRT74, K6IRS4, KB37, KRT5C, KRT6IRS4
Note Centrifuge prior to opening
Tested applications Tested dilutions
Immunohistochemistry (IHC) - frozen 1:100
Immunohistochemistry (IHC) - paraffin 1:50 (microwave treatment recommended)
Western Blot (WB) 1:1,500-1:5,000

Basic keratin K5 (Mr 58,000; formerly also designated cytokeratin 5), expressed in basal and first suprabasal layers of epidermis. Highly specific staining pattern in human and murine skin sections.
Tumors Specifically Detected: The antiserum reacts with keratin K5, expressed in the basal cells of the larynx, esophagus, trachea, bladder, cervix, vagina, breast acini, skin and sweat glands.
In several studies the correlation between the expression of keratin K5 in different types of carcinomas (putatively derived from basal epithelial cells) and prognosis has been discussed (see publications).


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