Custom service : Protein production and purification in mammalian cells
Use of a mammalian model, in comparison with a primary eukaryotic model, allows to mimic more the post-traductional modifications of proteins, essentials to their functions.
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Indeed, all of these modifications belong to the normal maturation process that give a well-structured recombinant protein whom physical properties are different than just the gene-encoded protein.
These modifications, among others, are glycosylation, cleavage, methylation etc…
This prestation is usually ensured from CHO cells (Chinese Hamster Ovarian cells).
=> Gene synthesis
=> Gene cloning
=> Polyclonals production
=> Monoclonals production