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> Cholesterol (Water Soluble)

Cholesterol (Water Soluble)

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Cat# HY-N0322A-50mg

Size : 50mg

Brand : MedChemExpress


Cholesterol Water Soluble can be used for the research of the effects of cholesterol on the potassium currents in inner hair cells (IHCs). Cholesterol is an integral component of the cell membrane and regulates the activity of ion channels in the lipid bilayer.

For research use only. We do not sell to patients.

Cholesterol (Water Soluble) Chemical Structure

Cholesterol (Water Soluble) Chemical Structure

This product is a controlled substance and not for sale in your territory.

Based on 20 publication(s) in Google Scholar

Other Forms of Cholesterol (Water Soluble):

  • Cholesterol In-stock
Description

Cholesterol Water Soluble can be used for the research of the effects of cholesterol on the potassium currents in inner hair cells (IHCs). Cholesterol is an integral component of the cell membrane and regulates the activity of ion channels in the lipid bilayer[1][2].

In Vitro

In solution of 1mM water-soluble cholesterol, the amplitude of K currents in isolated IHCs is reversely changed[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cholesterol (Water Soluble) Related Antibodies
Appearance

Solid

Color

White to off-white

SMILES

[Cholesterol-Water Soluble]
Structure Classification
  • Steroids
Initial Source
  • Endogenous metabolite
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (Need ultrasonic)

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 33.33 mg/mL (Infinity mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

  • [1]. Kimitsuki T. Cholesterol influences potassium currents in inner hair cells isolated from guinea pig cochlea. Auris Nasus Larynx. 2017;44(1):46-51.  [Content Brief]

    [2]. Nguyen TV, et al. Contribution of membrane cholesterol to outer hair cell lateral wall stiffness. Otolaryngol Head Neck Surg. 1998;119(1):14-20.  [Content Brief]

  • [1]. Kimitsuki T. Cholesterol influences potassium currents in inner hair cells isolated from guinea pig cochlea. Auris Nasus Larynx. 2017;44(1):46-51.

    [2]. Nguyen TV, et al. Contribution of membrane cholesterol to outer hair cell lateral wall stiffness. Otolaryngol Head Neck Surg. 1998;119(1):14-20.

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Cholesterol (Water Soluble) Related Classifications

Help & FAQs

Keywords:

Cholesterol (Water Soluble)LiposomeinnerhaircellslateralwallstiffnessInhibitorinhibitorinhibit

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