Rat VDR (Vitamin D Receptor) Sandwich ELISA Kit

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	Vdr
Gene ID:	24873
Uniprot ID:	VDR_RAT
Sample Type:	tissue homogenates, cell lysates or other biological fluids.

Tissue Specificity	Detected in intestine and kidney.
Post Translational Modifications
Function	Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells. Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR. The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes. Plays a central role in calcium homeostasis. Also functions as a receptor for the secondary bile acid lithocholic acid (LCA) and its metabolites.
Protein Name	Vitamin D3 Receptor Vdr 1 -25-Dihydroxyvitamin D3 Receptor Nuclear Receptor Subfamily 1 Group I Member 1
Database Links	Reactome: R-RNO-196791 Reactome: -RNO-383280 Reactome: -RNO-4090294
Cellular Localisation	Nucleus Cytoplasm Localizes Mainly To The Nucleus Translocated Into The Nucleus Via Both Ligand-Dependent And Ligand-Independent Pathways Ligand-Independent Nuclear Translocation Is Mediated By Ipo4
Alternative ELISA Names	Vitamin D3 Receptor ELISA kit Vdr ELISA kit 1 -25-Dihydroxyvitamin D3 Receptor ELISA kit Nuclear Receptor Subfamily 1 Group I Member 1 ELISA kit Vdr ELISA kit Nr1i1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance