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> 3-demethylcolchicine [7336-33-6]

3-demethylcolchicine [7336-33-6]

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Cat# TN6706-25mg

Size : 25mg

Brand : TargetMol


3-demethylcolchicine

Catalog No. TN6706   CAS 7336-33-6

3-demethylcolchicine is a natural product isolated from Gloriosa superba.Inhibitory effect on the polymerization of purified bovine brain tubulin.

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3-demethylcolchicine Chemical Structure
3-demethylcolchicine, CAS 7336-33-6
Description 3-demethylcolchicine is a natural product isolated from Gloriosa superba.Inhibitory effect on the polymerization of purified bovine brain tubulin.
In vitro 3-demethylcolchicine showed an appreciable effect in vitro and in vivo, in the lymphocytic leukemia P388 screen in mice, for their toxicity in mice, and for their binding to microtubule protein.
Molecular Weight 385.41
Formula C21H23NO6
CAS No. 7336-33-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 10 mg/mL (25.95 mM)

TargetMolReferences and Literature

1. M Rösner, H G Capraro, A E Jacobson.et al. Biological effects of modified colchicines. Improved preparation of 2-demethylcolchicine, 3-demethylcolchicine, and (+)-colchicine and reassignment of the position of the double bond in dehydro-7-deacetamidocolchicines.J Med Chem. 1981 Mar;24(3):257-61.