ML-7 HCl [110448-33-4]

Cat# AOB2530-25

Size : 25mg

Brand : AOBIOUS

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ML-7 HCl

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Data sheet

Molecular FormulaC15H18ClIN2O2S
Molecular Weight452.74
CAS Numbers110448-33-4
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
IUPAC/Chemical Name1-(5-Iodonaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride
SMILES CodeO=S(N1CCNCCC1)(C2=C3C=CC=C(I)C3=CC=C2)=O.19Cl
References1) Shi J, et al. Myosin light chain kinase-independent inhibition by ML-9 of murine TRPC6 channels expressed in HEK293cells. Br J Pharmacol. 2007 Sep;152(1):122-31.2) Yu J, et al. Dexmedetomidine-Induced Contraction in the Isolated Endothelium-Denuded Rat Aorta Involves PKC-δ-mediated JNK Phosphorylation. Int J Med Sci. 2015 Sep 4;12(9):727-363) Luh C, et al. Inhibition of myosin light chain kinase reduces brain edema formation after traumatic brain injury. J Neurochem. 2010 Feb;112(4):1015-25.

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Selective myosin light chain kinase inhibitor