ML-7 HCl [110448-33-4]
Cat# AOB2530-25
Size : 25mg
Brand : AOBIOUS

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Data sheet
Molecular Formula | C15H18ClIN2O2S |
Molecular Weight | 452.74 |
CAS Numbers | 110448-33-4 |
Storage Condition | 0°C (short term), -20°C (long term), desiccated |
Solubility | DMSO |
Purity | 98% by HPLC |
IUPAC/Chemical Name | 1-(5-Iodonaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride |
SMILES Code | O=S(N1CCNCCC1)(C2=C3C=CC=C(I)C3=CC=C2)=O.19Cl |
References | 1) Shi J, et al. Myosin light chain kinase-independent inhibition by ML-9 of murine TRPC6 channels expressed in HEK293cells. Br J Pharmacol. 2007 Sep;152(1):122-31.2) Yu J, et al. Dexmedetomidine-Induced Contraction in the Isolated Endothelium-Denuded Rat Aorta Involves PKC-δ-mediated JNK Phosphorylation. Int J Med Sci. 2015 Sep 4;12(9):727-363) Luh C, et al. Inhibition of myosin light chain kinase reduces brain edema formation after traumatic brain injury. J Neurochem. 2010 Feb;112(4):1015-25. |
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Selective myosin light chain kinase inhibitor