General Info
| Applications: | ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.146ng/mL |
| Detection Limit: | 0.312-20ng/mL |
| Short Description: | This DAB1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
Information
| Gene Symbol: | Dab1 |
| Gene ID: | 13131 |
| Uniprot ID: | DAB1_MOUSE |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | tissue homogenates or other biological fluids. |
Description
| Tissue Specificity | Expressed mainly in brain. |
| Post Translational Modifications | Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons. Also found phosphorylated on Tyr-232 upon reelin induction. Also phosphorylated on Ser-524 independently of reelin signaling. |
| Function | Adapter molecule functioning in neural development. May regulate SIAH1 activity. |
| Protein Name | Disabled Homolog 1 |
| Database Links | Reactome: R-MMU-8866376 |
| Cellular Localisation | |
| Alternative ELISA Names | Disabled Homolog 1 ELISA kitDab1 ELISA kit |
| output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance