NTRK2, Recombinant, Human, aa32-430, His-Tag (BDNF/NT-3 growth factors Receptor, GP145-TrkB, Trk-B, TRKB)

NTRK2, also known as BDNF/NT-3 growth factors receptor, is a receptor tyrosine kinase involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity. It plays a role in learning and memory by regulating both short term synaptic function and long-term potentiation.||Source:|Recombinant protein corresponding to aa32-430 from human NTRK2, fused to His-tag at C-terminal expressed in insect cell.||Molecular Weight: |~45.2kD (407aa)||Amino Acid Sequence:|CPTSCKCSAS RIWCSDPSPG IVAFPRLEPN ELILVGNPFT CSCDIMWIKT LQEAKSSPDT ITNISSDDSG KQISCVAENL VGEDQDSVNL IAKNEYGKDE KQISAHFMGW PGIDDGANPN|SVDPENITEI FIANQKRLEI INEDDVEAYV GLRNLTIVDS GLKFVAHKAF LKNSNLQHIN FTRNKLTSLS RKHFRHLDLS QDLYCLNESS KNIPLANLQI PNCGLPSANL AAPNLTVEEG KSITLSCSVA GDPVPNMYWD VGNLVSKHMN ETSHTQGSLR TVHFAPTITF LESPTSDHHW CIPFTVKGNP KPALQWFYNG AILNESKYIC TKIHVTNHTE YHGCLQLDNP THMNNGDYTL YPDVIYEDYG TAANDIGDTT NRSNEIPSTD VTDKTGREHL EHHHHHH||Endotoxin: ~1EU/1ug (LAL)||Storage and Stability:|May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.