RNase H1 Positive Control

Cat# NB-22-77329-5

Size : 5applications

Brand : Neo Biotech


General Info

Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: RNase H1 Positive Control for STJ506225 is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Information

Gene Symbol: RNASEH1
Gene ID: 246243
Uniprot ID: RNH1_HUMAN
Specificity: This is positive control is recommended for use in combination with RNase H1 antibody STJ506225.

Description

Function Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II.
Peptide Name Ribonuclease H1
Rnase H1
Ribonuclease H Type Ii
Cellular Localisation Cytoplasm
Alternative Peptide Names Ribonuclease H1 protein
Rnase H1 protein
Ribonuclease H Type Ii protein
RNASEH1 protein
RNH1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance