- Specifications
Product Description
Mouse monoclonal antibody raised against native ICAM1.
Immunogen
Native purified ICAM1 from Raji Burkitt's lymphoma cell line.
Host
Mouse
Theoretical MW (kDa)
85-110
Reactivity
Bovine, Human, Rat
Specificity
This antibody reacts with CD54 (ICAM-1), a 85-110 KDa type I transmembrane glycoprotein (receptor for rhinovirus). The expression of CD54 is upregulated by activation; it is expressed on activated endothelial cells, T lymphocytes, B lymphocytes, monocytes, macrophages, granulocytes and dendritic cells.
Form
Liquid
Conjugation
PE
Isotype
IgG2a
Recommend Usage
Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.2% BSA, 0.09% sodium azide)
Storage Instruction
Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
Flow Cytometry
- Gene Info — ICAM1
Entrez GeneID
3383Gene Name
ICAM1
Gene Alias
BB2, CD54, P3.58
Gene Description
intercellular adhesion molecule 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq
Other Designations
cell surface glycoprotein P3.58|human rhinovirus receptor|intercellular adhesion molecule 1 (CD54), human rhinovirus receptor
- Interactomes
- Pathways
- Diseases
- Publication Reference
- Susceptibility of immature and mature Langerhans cell-type dendritic cells to infection and immunomodulation by human cytomegalovirus.
Hertel L, Lacaille VG, Strobl H, Mellins ED, Mocarski ES.
Journal of Virology 2003 Jul; 77(13):7563.
Application：Flow Cyt, Mouse, Dendritic cells.
- Colon carcinoma cell glycolipids, integrins, and other glycoproteins mediate adhesion to HUVECs under flow.
Burdick MM, McCaffery JM, Kim YS, Bochner BS, Konstantopoulos K.
American Journal of Physiology. Cell Physiology 2002 Dec; 284(4):C977.
Application：IEM, Human, HUVEC, LS174T cells.
- Eotaxin-2 alters eosinophil integrin function via mitogen-activated protein kinases.
Tachimoto H, Kikuchi M, Hudson SA, Bickel CA, Hamilton RG, Bochner BS.
American Journal of Respiratory Cell and Molecular Biology 2002 Jun; 26(6):645.
Application：ELISA, Human, Eosinophils.
- Molecular mechanisms of improved adhesion and growth of an endothelial cell line cultured on polystyrene implanted with fluorine ions.
Bacáková L, Mares V, Lisá V, Svorcík V.
Biomaterials 2000 Jun; 21(11):1173.
Application：ELISA, Cow, CPAE cells.
- Fluorine ion-implanted polystyrene improves growth and viability of vascular smooth muscle cells in culture.
Bacáková L, Mares V, Bottone MG, Pellicciari C, Lisá V, Svorcík V.
Journal of Biomedical Materials Research 2000 Mar; 49(3):369.
Application：IF, Rat, Aortic smooth muscle cells.
- Susceptibility of immature and mature Langerhans cell-type dendritic cells to infection and immunomodulation by human cytomegalovirus.
ICAM1 monoclonal antibody, clone MEM-111 (PE)
Cat# MAB4641
Size : 100Reactions