General Info
Applications: | ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.18ng/mL |
Detection Limit: | 0.468-30ng/mL |
Short Description: | This FCN1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Information
Gene Symbol: | Fcn1 |
Gene ID: | 14133 |
Uniprot ID: | FCN1_MOUSE |
Sample Type: | serum, plasma, tissue homogenates or other biological fluids. |
Description
Tissue Specificity | Highly expressed in liver and spleen. |
Post Translational Modifications | |
Function | Extracellular lectin functioning as a pattern-recognition receptor in innate immunity. Binds the sugar moieties of pathogen-associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of the complement system. May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8. Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage. |
Protein Name | Ficolin-1Collagen/Fibrinogen Domain-Containing Protein 1Ficolin-AFicolin-AlphaM-Ficolin |
Database Links | Reactome: R-MMU-166662Reactome: -MMU-166663Reactome: -MMU-2855086Reactome: -MMU-6798695 |
Cellular Localisation | SecretedCell MembranePeripheral Membrane ProteinExtracellular SideFound On The Monocyte And Granulocyte Surface |
Alternative ELISA Names | Ficolin-1 ELISA kitCollagen/Fibrinogen Domain-Containing Protein 1 ELISA kitFicolin-A ELISA kitFicolin-Alpha ELISA kitM-Ficolin ELISA kitFcn1 ELISA kitFcna ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance