Paclobutrazol [76738-62-0]
Cat# HY-B0853-250mg
Size : 250mg
Brand : MedChemExpress
Paclobutrazol is a triazole-containing plant growth retardant that is known to inhibit the biosynthesis of gibberellins. Paclobutrazol also has antifungal activities. Paclobutrazol, transported acropetally in plants, can also suppress the synthesis of abscisic acid and induce chilling tolerance in plants. Paclobutrazol is typically used to support research on the role of gibberellins in plant biology.
For research use only. We do not sell to patients.
Paclobutrazol Chemical Structure
CAS No. : 76738-62-0
This product is a controlled substance and not for sale in your territory.
Based on 1 publication(s) in Google Scholar
Other Forms of Paclobutrazol:
- (Rac)-Paclobutrazol-15N3 Get quote
- Paclobutrazol-d4 Get quote
Description |
Paclobutrazol is a triazole-containing plant growth retardant that is known to inhibit the biosynthesis of gibberellins. Paclobutrazol also has antifungal activities. Paclobutrazol, transported acropetally in plants, can also suppress the synthesis of abscisic acid and induce chilling tolerance in plants. Paclobutrazol is typically used to support research on the role of gibberellins in plant biology[1][2]. |
||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
In Vitro |
Paclobutrazol (Foliar spraying, 5-20 μg/mL) increases total soluble sugars, starch, protein and free amino acids in mature seeds of Brassica juncea[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |
||||||||||||
Molecular Weight |
293.79 |
||||||||||||
Formula |
C15H20ClN3O |
||||||||||||
CAS No. |
76738-62-0 |
||||||||||||
Unlabeled Cas |
|
||||||||||||
Appearance |
Solid |
||||||||||||
Color |
White to off-white |
||||||||||||
SMILES |
O[C@@H](C(C)(C)C)[C@@H](N1N=CN=C1)CC2=CC=C(Cl)C=C2 |
||||||||||||
Shipping | Room temperature in continental US; may vary elsewhere. |
||||||||||||
Storage |
4°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) |
||||||||||||
Solvent & Solubility |
In Vitro:
DMSO : 250 mg/mL (850.95 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) Preparing
Stock Solutions
View the Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO
+
%
+
%
Tween-80
+
%
Saline
The co-solvents required include: DMSO,
. All of co-solvents are available by MedChemExpress (MCE).
, Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Calculation results:
Working solution concentration:
mg/mL
Method for preparing stock solution:
mg
drug dissolved in
μL
DMSO (Stock solution concentration: mg/mL).
*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
Method for preparing in vivo working solution for animal experiments: Take
μL DMSO stock solution, add
μL .
μL , mix evenly, next add
μL Tween 80, mix evenly, then add
μL Saline.
If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
|
||||||||||||
Purity & Documentation |
Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
---|
DMSO | 1 mM | 3.4038 mL | 17.0190 mL | 34.0379 mL | 85.0948 mL |
5 mM | 0.6808 mL | 3.4038 mL | 6.8076 mL | 17.0190 mL | |
10 mM | 0.3404 mL | 1.7019 mL | 3.4038 mL | 8.5095 mL | |
15 mM | 0.2269 mL | 1.1346 mL | 2.2692 mL | 5.6730 mL | |
20 mM | 0.1702 mL | 0.8509 mL | 1.7019 mL | 4.2547 mL | |
25 mM | 0.1362 mL | 0.6808 mL | 1.3615 mL | 3.4038 mL | |
30 mM | 0.1135 mL | 0.5673 mL | 1.1346 mL | 2.8365 mL | |
40 mM | 0.0851 mL | 0.4255 mL | 0.8509 mL | 2.1274 mL | |
50 mM | 0.0681 mL | 0.3404 mL | 0.6808 mL | 1.7019 mL | |
60 mM | 0.0567 mL | 0.2836 mL | 0.5673 mL | 1.4182 mL | |
80 mM | 0.0425 mL | 0.2127 mL | 0.4255 mL | 1.0637 mL | |
100 mM | 0.0340 mL | 0.1702 mL | 0.3404 mL | 0.8509 mL |