Anti-Frizzled 2 (FZD2) Polyclonal Antibody

This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. This gene encodes a protein that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways.||Applications:|Suitable for use in Immunoprecipitation and Western Blot. Other applications have not been tested.||Recommended Dilution:|Immunoprecipitation: 7ug/reaction|Western Blot: 1-3ug/ml|Optimal dilutions to be determined by the researcher.||Positive Controls:|Immunoprecipitation: HepG2 cells |Western Blot: Human CaCO2, PC-3, SKOV3, SW480, HepG2 and HEK293 cell lysates||Storage and Stability:|May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.