Cholesterol-d7 [83199-47-7]
Cat# HY-N0322S-10mg
Size : 10mg
Brand : MedChemExpress
Cholesterol-d7 is the deuterium labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist.
For research use only. We do not sell to patients.
Cholesterol-d7 Chemical Structure
CAS No. : 83199-47-7
This product is a controlled substance and not for sale in your territory.
Based on 1 publication(s) in Google Scholar
Other Forms of Cholesterol-d7:
- Cholesterol In-stock
- Cholesterol-d6 In-stock
Description |
Cholesterol-d7 is the deuterium labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins[1][2]. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist[3]. |
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In Vitro |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |
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Molecular Weight |
393.70 |
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Formula |
C27H39D7O |
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CAS No. |
83199-47-7 |
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Appearance |
Solid |
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Color |
White to off-white |
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SMILES |
C[C@@H]([C@]1(CC[C@]2([C@@]3(CC=C4C[C@H](CC[C@@]4([C@]3(CC[C@@]21C)20)C)O)20)20)20)CCCC([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H] |
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Shipping | Room temperature in continental US; may vary elsewhere. |
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Storage |
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Solvent & Solubility |
In Vitro:
Ethanol : 20 mg/mL (50.80 mM; Need ultrasonic and warming) Preparing
Stock Solutions
View the Complete Stock Solution Preparation Table
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Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration:
mg/mL
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Purity & Documentation |
Purity: 98.29% |
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References |
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Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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Ethanol | 1 mM | 2.5400 mL | 12.7000 mL | 25.4001 mL | 63.5001 mL |
5 mM | 0.5080 mL | 2.5400 mL | 5.0800 mL | 12.7000 mL | |
10 mM | 0.2540 mL | 1.2700 mL | 2.5400 mL | 6.3500 mL | |
15 mM | 0.1693 mL | 0.8467 mL | 1.6933 mL | 4.2333 mL | |
20 mM | 0.1270 mL | 0.6350 mL | 1.2700 mL | 3.1750 mL | |
25 mM | 0.1016 mL | 0.5080 mL | 1.0160 mL | 2.5400 mL | |
30 mM | 0.0847 mL | 0.4233 mL | 0.8467 mL | 2.1167 mL | |
40 mM | 0.0635 mL | 0.3175 mL | 0.6350 mL | 1.5875 mL | |
50 mM | 0.0508 mL | 0.2540 mL | 0.5080 mL | 1.2700 mL |
Cholesterol-d7 Related Classifications
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Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.
Keywords:
Cholesterol-d783199-47-7Estrogen Receptor/ERREndogenous MetaboliteInhibitorinhibitorinhibit