Specifications

Product Data
Applications	IHC
Recommended Dilution	IHC: 50-200 Positive control: Human colon cancer Predicted cell location: Cytoplasm, Cell membrane
Reactivities	Human
Host	Rabbit
Isotype	IgG
Clonality	Polyclonal
Immunogen	Synthetic peptide peptide corresponding to a region derived from 466-479 amino acids of human solute carrier family 2 (facilitated glucose transporter), member 3
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage	Store at -20°C as received.
Stability	Stable for 12 months from date of receipt.
Gene Name	solute carrier family 2 member 3
Database Link	NP_008862 Entrez Gene 6515 Human UniProt ID P11169
Background	Glucose transporter 3?(or?GLUT3); also known as?solute carrier family 2; facilitated glucose transporter member 3?(SLC2A3) is a?protein?that in humans is encoded by the?SLC2A3?gene. GLUT3?facilitates?the transport ofglucose?across the?plasma membranes?of mammalian cells. GLUT3 is most known for its specific expression in?neurons?and has originally been designated as the neuronal GLUT. GLUT3 has been studied in other cell types with specific glucose requirements; including?sperm; preimplantation?embryos; circulating?white blood cells?and?carcinoma?cell lines. GLUT3 has both a higher affinity for glucose and at least a fivefold greater transport capacity than GLUT1; GLUT2 and GLUT4; which is particularly significant for its role in neuronal glucose transport; where ambient glucose levels are fivefold lower than in serum.
Synonyms	GLUT3
Reference Data
Protein Families	Transmembrane