Human Cytochrome C (CYCS) activation kit by CRISPRa

CAT#: GA110072

CYCS CRISPRa kit - CRISPR gene activation of human cytochrome c, somatic



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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol CYCS
Locus ID 54205
Kit Components

GA110072G1, Cytochrome C gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA110072G2, Cytochrome C gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA110072G3, Cytochrome C gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_018947
UniProt ID P99999
Synonyms CYC; HCS; THC4
Summary This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome.[provided by RefSeq, Jul 2010]

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