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> Reversine [656820-32-5]

Reversine [656820-32-5]

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Cat# 10-1154-5mg

Size : 5mg

Brand : Focus Biomolecules


Reversine | Reverses differentiated cells to multipotent stem cells

CAS:
656820-32-5
Catalog Number:
10-1154
Activity:
Reverses differentiated cells to multipotent stem cells
Chemical Name:
2-(4-Morpholinoanilino)-6-cyclohexylaminopurine
Molecular Weight:
383.5
Molecular Formula:
C21H27N7O
Solubility:
Soluble in DMSO (up to 7 mg/ml).
Physical Properties:
Off-white solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months
Shipping Code:
RT

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5 mg$75.00
25 mg$170.00
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Reversine (656820-32-5) induces differentiated myogenic-lineage-committed cells to become multipotent mesenchymal progenitor cells.1,2 Acts as a selective human A3 adenosine receptor antagonist (Ki = 0.66 μM).3 Cell permeable.

References/Citations:

1) Chen et al. (2004), Dedifferentiation of lineage-committed cells by a small molecule; J. Am. Chem. Soc., 126 410
2) Chen et al. (2007), Reversine increases the plasticity of lineage-committed mammalian cells; Proc. Natl. Acad. Sci. USA, 104 10482
3) Perreira et al. (2005), Reversine and its 2-substituted adenine derivatives as potent and selective A3 adenosine receptor antagonists; J. Med. Chem., 48 4910

CAS:
656820-32-5
Catalog Number:
10-1154
Activity:
Reverses differentiated cells to multipotent stem cells
Chemical Name:
2-(4-Morpholinoanilino)-6-cyclohexylaminopurine
Molecular Weight:
383.5
Molecular Formula:
C21H27N7O
Solubility:
Soluble in DMSO (up to 7 mg/ml).
Physical Properties:
Off-white solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

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Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a restocking/refund fee

Reversine (656820-32-5) induces differentiated myogenic-lineage-committed cells to become multipotent mesenchymal progenitor cells.1,2 Acts as a selective human A3 adenosine receptor antagonist (Ki = 0.66 μM).3 Cell permeable.

References/Citations:

1) Chen et al. (2004), Dedifferentiation of lineage-committed cells by a small molecule; J. Am. Chem. Soc., 126 410
2) Chen et al. (2007), Reversine increases the plasticity of lineage-committed mammalian cells; Proc. Natl. Acad. Sci. USA, 104 10482
3) Perreira et al. (2005), Reversine and its 2-substituted adenine derivatives as potent and selective A3 adenosine receptor antagonists; J. Med. Chem., 48 4910