Reagents and instruments for immunology, cell biology and molecular biology.

Spectinomycin-2HCl pentahydrate

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Cat# 35294.01

Size : 5G

Brand : SERVA Electrophoresis

(Actinospectacin; M 141)
C₁₄H₂₄N₂O₇·2HCl·5H₂O • M_r 495.4 • CAS [22189-32-8]

Cell culture tested.
Water-soluble aminoglycoside antibiotic from Streptomyces sp. (1,2). Inhibitor of protein synthesis (3). Differs from other aminoglycoside derivatives in that it is bacteriostatic instead of bactericidal.
Stock solution: 10 mg/ml in distilled water, sterile filtered.
For molecular biology applications standard working concentration is 100 µg/ml and in cell culture 7.5 – 20 mg/l.

References:

Wagner J. G. et al. (1968) Int. Z. Klin. Pharmakol. Ther. Toxikol. 1, 261 – 85
Wallace, B.J. et al. (1979) Antibiotics 5, 272 – 303
Wallace, P.-C. et al. (1979) in Antibiotics, vol. V, part I. Mechanism of Action of Antibacterial Agents, Springer Verlag Berlin