Lipid 121 is an amino lipid which has a long (11 carbons) lipid tail on the primary ester located at C7 relative to nitrogen amine. The head contains ethanolamine which can efficiently encapsulate mRNA. The secondary ester is introduced, on the ester located at C8 position relative to amine, to improve protein expression in the liver. The lipid can be used to prepare mRNA nanocarriers with good balance of delivery efficiency and pharmakokinetics as well as rapid lipid clearance profile. Reagent grade, for research purpose.
Cat# orb1910791-100mg
Size : 100mg
Brand : Biorbyt
BP Lipid 121
Catalog Number: orb1910791
| Catalog Number | orb1910791 |
|---|---|
| Category | Small Molecules |
| Description | Lipid 121 is an amino lipid which has a long (11 carbons) lipid tail on the primary ester located at C7 relative to nitrogen amine. The head contains ethanolamine which can efficiently encapsulate mRNA. The secondary ester is introduced, on the ester located at C8 position relative to amine, to improve protein expression in the liver. The lipid can be used to prepare mRNA nanocarriers with good balance of delivery efficiency and pharmakokinetics as well as rapid lipid clearance profile. Reagent grade, for research purpose. |
| MW | 724.2 |
| SMILES | OCCN(CCCCCCCC(OC(CCCCCCCC)CCCCCCCC)=O)CCCCCCC(OCCCCCCCCCCC)=O |
| Formula | C45H89NO5 |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |