MDC1 antibody
Cat# orb148046-100ug
Size : 100ug
Brand : Biorbyt
MDC1 antibody
Catalog Number: orb148046
| Catalog Number | orb148046 |
|---|---|
| Category | Antibodies |
| Description | Mouse monoclonal to MDC1 (PerCP). MDC1, mediator of DNA damage checkpoint protein 1, plays a role in checkpoint mediated cell cycle arrest in response to DNA damage, within S phase and G2/M. It is also thought to act as a scaffold protein during recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage that are marked by phosphorylation of histone H2A. X on S139.. |
| Species/Host | Mouse |
| Clonality | Monoclonal |
| Clone Number | P2B11 |
| Tested applications | ICC, WB |
| Reactivity | Bovine, Human, Mouse, Primate |
| Isotype | IgG1 |
| Immunogen | GST-tagged recombinant protein corresponding to mouse MDC1 at and around the N-terminus |
| Concentration | 1 mg/ml |
| Dilution range | WB (1:2000), ICC/IF (1:100) |
| Conjugation | PerCP |
| MW | 184kDa |
| Target | MDC1 |
| Entrez | 240087 |
| UniProt ID | Q5PSV9 |
| NCBI | NP_001010833.2 |
| Storage | Conjugated antibodies should be stored at 4°C |
| Buffer/Preservatives | PBS pH 7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated |
| Alternative names | Nuclear factor with BRCT domains1 antibody, mediat |
| Note | For research use only |
| Application notes | 0.5 µg/ml of SMC-197 was sufficient for detection of MDC1 in 10 µg of HeLa cell lysate by ECL immunoblot analysis. |
| Expiration Date | 12 months from date of receipt. |